Evidence map›Paper›PMID 41954664›Full record

ArticleArchives of orthopaedic and trauma surgery2026

Comparative assessment of the reaming characteristics of two different technologies for intramedullary bone graft harvesting.

Simone Guttau, Merle Lange, Ronja Finze, Claudia Beimel, Siamak Saifzadeh, Jonathan Gospos, Marie-Luise Wille, Philipp Kobbe, Markus Laubach

Abstract readComparative Study
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simone Guttau *Stryker Trauma GmbH, Schönkirchen, Germany. Simone.Guttau@stryker.com.
Merle Lange *Stryker Trauma GmbH, Schönkirchen, Germany.
Ronja FinzeDepartment of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Heidelberg University, Ludwigshafen, Germany.
Claudia BeimelStryker Trauma GmbH, Schönkirchen, Germany.
Siamak SaifzadehAustralian Research Council (ARC) Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing (M3D Innovation), Queensland University of Technology, Queensland, 4000, Brisbane, Australia.ORCID http://orcid.org/0000-0002-0295-7477
Jonathan GosposMax Planck Queensland Centre (MPQC) for the Materials Science of Extracellular Matrices, Queensland University of Technology (QUT), Queensland, 4000, Brisbane, Australia.ORCID http://orcid.org/0009-0005-3836-9852
Marie-Luise WilleAustralian Research Council (ARC) Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing (M3D Innovation), Queensland University of Technology, Queensland, 4000, Brisbane, Australia.ORCID http://orcid.org/0000-0003-4962-7587
Philipp KobbeDepartment for Trauma and Reconstructive Surgery, University Hospital of the Martin Luther University Halle, Halle (Saale), Germany.
Markus LaubachAustralian Research Council (ARC) Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing (M3D Innovation), Queensland University of Technology, Queensland, 4000, Brisbane, Australia. markus.laubach@med.uni-muenchen.de.ORCID http://orcid.org/0000-0002-3451-1445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe study aimed to compare the biomechanical impact and reaming performance of two intramedullary bone graft harvesting techniques: the established Reamer-Irrigator-Aspirator 2 (RIA 2) system and a novel aspirator+reaming-aspiration (ARA) concept. MATERIALS AND

methodsIn a preclinical in vivo sheep model, sixteen femora were assigned to either the RIA 2 or ARA group (n = 8 each). Biomechanical testing, computed tomography (CT)-based 3D bone geometry analysis, and fracture line assessment were performed postoperatively. Bending stiffness of the reamer shafts, cortical wall thickness pre- and post-reaming, and torsional stability of reamed femora were evaluated. Statistical analysis included TOST, Mann-Whitney U, and Shapiro-Wilk tests, considering values of p < 0.05 as statistically significant.

resultsBoth reaming systems produced the greatest cortical thinning medially in the midsections of the analyzed region. No statistically significant differences were observed in postoperative cortical wall thickness, bone removal rates, or torsional stability between groups (all p > 0.05). Bending stiffness was significantly higher for the RIA 2 system (p = 0.004). In both groups, fractures predominantly initiated medially or at sites of previous drill holes. The ARA concept demonstrated equivalent biomechanical and reaming performance compared to the RIA 2 system, with a comparable safety profile.

conclusionsIn this preclinical in vivo comparison, the RIA 2 system and the ARA concept with BixCut reamers demonstrated equivalent reaming performance regarding cortical bone removal and femoral shaft geometry. Although the RIA 2 drive shaft exhibited greater bending stiffness, both systems induced comparable medial cortical thinning in the mid-diaphyseal region. Three-dimensional geometric analysis and ex vivo biomechanical testing showed no significant differences in residual cortical thickness or torsional stability. Fracture patterns were similar and correlated with areas of maximal medial thinning. Overall, both systems provided comparable reaming functionality and biomechanical outcomes.

Indexed as

Bone TransplantationFemurTissue and Organ HarvestingAnimalsBiomechanical PhenomenaSheepARA conceptIntramedullary reamingin vivoRIA 2 system

Identifiers

PMID41954664
PMCPMC13065597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.