Evidence map›Paper›PMID 41954213›Full record

ArticleJournal of medical virology2026

Evaluation of a New Automated Platform for the Detection and Quantification of HEV RNA.

Mélanie Lecrac, Sébastien Lhomme, Aurélie Guigon, Benoit Visseaux, Céline Delevallée, Stéphanie Haïm-Boukobza, Xavier Huc, Annlyse Esteban, Soheil Elhayani, Jacques Izopet and 1 more

Abstract readEvaluation StudyComparative Study
In one paragraph

Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mélanie LecracHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.
Sébastien LhommeHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.ORCID https://orcid.org/0000-0001-7908-1576
Aurélie GuigonCHU de Lille, Laboratoire de Virologie, Lille, Cedex, France.
Benoit VisseauxDépartement d'Infectiologie, Laboratoire Cerba, Cerba Healthcare, Frépillon, France.
Céline DelevalléeLaboratoire INOVIE Gen-Bio Gravanches, 8, rue Jacqueline Auriol, Clermont-Ferrand, France.
Stéphanie Haïm-BoukobzaDépartement d'Infectiologie, Laboratoire Cerba, Cerba Healthcare, Frépillon, France.
Xavier HucLaboratoire INOVIE Gen-Bio Gravanches, 8, rue Jacqueline Auriol, Clermont-Ferrand, France.
Annlyse EstebanHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.
Soheil ElhayaniHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.
Jacques IzopetHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.
Florence AbravanelHôpital Purpan, Laboratoire de Virologie, Centre National de Référence pour la VHE, Toulouse, France.ORCID https://orcid.org/0000-0002-1753-1065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide. We evaluated the performance of the fully automated HEV RNA assay (HEV ELITe MGB® Kit) using the ELITe InGenius instrument. The limit of detection was established in line with the WHO standard (genotype 3a) and genotype 3f and 3c clinical samples. Finally, the analytical performance of the HEV ELITe MGB® Kit was compared with the Altostar® HEV RNA assay by testing 292 plasma samples and 10 stool samples. The ELITe tool utilized 200 µL of plasma or stool suspension eluted in 100 µL. Linearity was verified from 2 × 10

Indexed as

Automation, LaboratoryHepatitis EHepatitis E virusMolecular Diagnostic TechniquesRNA, ViralViral LoadFecesGenotypeHumansLimit of DetectionReagent Kits, DiagnosticSensitivity and SpecificityReagent Kits, DiagnosticRNA, ViralAltostarElite IngeniusHepatitis E virusplasmastool

Identifiers

PMID41954213
PMCPMC13063801

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.