Evidence map›Paper›PMID 41954067›Full record

ArticleJournal of the American Heart Association2026

Increased Risk of Disabilities in Children and Adolescents With Congenital Heart Disease of Any Severity.

Samantha J Lain, Wen-Qiang He, Gillian M Blue, David S Winlaw, Gary Sholler, Edwin P Kirk, Sally L Dunwoodie, David S Celermajer, Natasha Nassar

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha J LainChild Population and Translational Health Research, Children's Hospital at Westmead Clinical School The University of Sydney Sydney NSW Australia.ORCID 0000-0002-8988-7407
Wen-Qiang HeChild Population and Translational Health Research, Children's Hospital at Westmead Clinical School The University of Sydney Sydney NSW Australia.ORCID 0000-0002-7475-8485
Gillian M BlueHeart Centre for Children, Sydney Children's Hospital Network Children's Hospital at Westmead Sydney NSW Australia.ORCID 0000-0002-1480-9535
David S WinlawAnn and Robert H. Lurie Children's Hospital of Chicago, and Feinberg School of Medicine, Northwestern University Chicago IL USA.ORCID 0000-0001-8005-3361
Gary ShollerHeart Centre for Children, Sydney Children's Hospital Network Children's Hospital at Westmead Sydney NSW Australia.ORCID 0000-0003-1501-8898
Edwin P KirkSchool of Clinical Medicine, Faculty of Medicine and Health University of New South Wales Sydney NSW Australia.
Sally L DunwoodieVictor Chang Cardiac Research Institute Sydney NSW Australia.ORCID 0000-0002-2069-7349
David S CelermajerHeart Research Institute University of Sydney Sydney NSW Australia.ORCID 0000-0001-7640-0439
Natasha NassarChild Population and Translational Health Research, Children's Hospital at Westmead Clinical School The University of Sydney Sydney NSW Australia.ORCID 0000-0002-3720-9655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the prevalence of overall and specific disability service use among children with congenital heart disease (CHD) compared with matched controls and siblings.

methodsThis was a retrospective data-linkage study of children diagnosed with CHD (excluding chromosomal abnormality/syndrome and extracardiac congenital anomalies) in a hospital in New South Wales, Australia from 2002 to 2014. CHD was stratified into severity groups based on CHD diagnosis and age at cardiac procedure. Disability services data identified intellectual disability, autism, sensory, speech, learning, and physical disability. Multivariable logistic regression models, adjusted for clinical and sociodemographic factors, were used to examine odds of disability compared with children without CHD, with generalized estimating equations used in sibling models.

resultsThere were 4420 children with CHD, 37 931 without CHD, and 4606 siblings. The proportion receiving a disability service was 7.0% for severe CHD, 5.6% for other CHD with a cardiac procedure, and 5.1% for nonsevere CHD, compared with 2.5% children without CHD and 3.3% siblings. Adjusted odds ratios (aORs) of any disability service compared with those without CHD were as follows: severe CHD (aOR, 2.82 [95% CI, 2.19-3.63]), other CHD with a procedure (aOR, 2.20 [95% CI, 1.58-3.05]), and nonsevere CHD (aOR, 1.75 [95% CI, 1.42-2.15]). These associations remained in sibling analyses for severe CHD (aOR, 2.47 [95% CI, 1.57-3.88) and other CHD with a procedure (aOR, 1.63 [95% CI, 1.02-2.61]) but not nonsevere CHD.

conclusionsChildren with CHD, regardless of severity, had a significantly higher risk of receiving a disability service than the general population and a greater risk for those who had undergone a cardiac procedure compared with their siblings.

Indexed as

Children with DisabilitiesHeart Defects, CongenitalAdolescentChildChild, PreschoolDisability EvaluationFemaleHumansInfantIntellectual DisabilityLogistic ModelsMaleMultivariate AnalysisNew South WalesOdds RatioPrevalencecongenital heart diseasedisabilitypopulation research

Identifiers

PMID41954067
PMCPMC13279058

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.