ArticleJournal of the American Heart Association2026
Severe Aortic Stenosis Is Associated With Left Atrial Prothrombotic Flow That Persists Despite Valve Replacement.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cardiac imaging highlights from European Society of Cardiology 2024: the future is within our grasp!European heart journal. Imaging methods and practice · 2025Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere aortic stenosis (AS) is associated with ischemic stroke independently of atrial fibrillation or other causes. Even after aortic valve replacement (AVR), patients remain affected by a 6% 5-year stroke rate with knowledge gaps in the underlying pathophysiology. We hypothesize that severe AS is associated with prothrombotic left atrial (LA) flow changes that do not normalize after AVR.
methodsSeventy-seven participants without atrial fibrillation were recruited: 40 with severe AS (median age, 73 years; CHA
resultsCompared with controls, patients with severe AS displayed significantly higher left ventricular (LV) mass (
conclusionsPatients with severe AS display adverse prothrombotic LA flow characteristics that persist after successful AVR despite general regression of LV hypertrophy.
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