Evidence map›Paper›PMID 41953955›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2026

Monosubstituted N-Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds.

Michael G Kallitsakis, Kyriakos D Nikopoulos, Ioannis N Lykakis

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael G KallitsakisDepartment of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kyriakos D NikopoulosDepartment of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Ioannis N LykakisDepartment of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Funding

General Secretariat for Research and Innovation (GSRI)
6 · The paper itself

Abstract

Hydroxylamines represent a structurally diverse class of compounds encompassing both N- and/or O-substituted derivatives, each exhibiting distinct chemical reactivity and synthetic utility. Notably, N-arylhydroxylamines define a unique branch within the hydroxylamine family serving as key intermediates in redox transformations and as reactive platforms for diverse synthetic elaborations. Guided by the distinctive reactivity and unique features of this class, we propose a novel perspective that unifies synthetic approaches with application-driven insights, emphasizing the strategic significance of monosubstituted N-arylhydroxylamines as versatile building blocks for the construction of complex heterocyclic architectures and a range of valuable organic compounds. By merging recent advances in synthetic strategies with their practical applications, this review aims to provide a comprehensive account of the versatile role of this branch centered on N-arylhydroxylamine motifs in modern organic synthesis.

Indexed as

catalysisheterocyclesN‐arylhydroxylaminesreductionsynthesis

Identifiers

PMID41953955
PMCPMC13356364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.