Evidence map›Paper›PMID 41953872›Full record

ArticleJournal of medical cases2026

Complex Oncologic Surgery in a Nonagenarian With Severe Aortic Stenosis: Integration of Enhanced Recovery After Surgery Protocol, Total Intravenous Anesthesia, and Advanced Hemodynamic Monitoring.

Alert Drishti, Teuta Dedej-Kurti, Rudin Domi, Gentian Huti, Asead Abdyli, Driola Hoxha, Oliatina Demiri, Besnik Filaj, Diamant Lulaj, Krenar Lilaj and 5 more

Abstract readCase Reports
In one paragraph

Article in Journal of medical cases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alert DrishtiDepartment of Surgery, Clinical Toxicology Service, University of Medicine, Tirana, Albania.
Teuta Dedej-KurtiLaboratory Department, University of Medicine, Tirana, Albania.
Rudin DomiDepartment of Surgery, Service of Anesthesia and Intensive Care, University of Medicine, Tirana, Albania.
Gentian HutiDepartment of Anesthesiology and Intensive Care, American Hospital 3, Tirana, Albania.
Asead AbdyliDepartment of Anesthesiology and Intensive Care, American Hospital 3, Tirana, Albania.
Driola HoxhaDepartment of Anesthesiology and Intensive Care, American Hospital 3, Tirana, Albania.
Oliatina DemiriDepartment of Anesthesiology and Intensive Care, American Hospital 3, Tirana, Albania.
Besnik FilajDepartment of Anesthesiology and Intensive Care, American Hospital 3, Tirana, Albania.
Diamant LulajDepartment of Cardiology, American Hospital 3, Tirana, Albania.
Krenar LilajDepartment of Surgery, Service of Anesthesia and Intensive Care, University of Medicine, Tirana, Albania.
Majlinda NacoDepartment of Surgery, Service of Anesthesia and Intensive Care, University of Medicine, Tirana, Albania.
Alma CaniDepartment of Surgery, Service of Anesthesia and Intensive Care, University of Medicine, Tirana, Albania.
Hektor SulaDepartment of Surgery, Service of Anesthesia and Intensive Care, University of Medicine, Tirana, Albania.
Filadelfo ConiglioneDepartment of Clinical Science and Translational Medicine, Tor Vergata University of Rome, Rome, Italy.
Vedat EljeziDepartment of Perioperative Medicine, CHU Gabriel-Montpied, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of elderly patients presenting for major surgery is steadily increasing, and perioperative management in this population remains challenging because of frailty, multiple comorbidities, and reduced physiological reserve. Severe aortic stenosis represents a particularly high-risk condition due to fixed stroke volume and sensitivity to even brief episodes of hypotension or tachycardia. We describe the perioperative course of a 92-year-old woman who underwent combined right radical nephroureterectomy, cystectomy, and total hysterectomy with bilateral salpingo-oophorectomy, using a multimodal strategy that included total intravenous anesthesia, enhanced recovery after surgery principles, and advanced hemodynamic monitoring with MOSTCARE. Despite considerable cardiovascular and surgical risk, intraoperative hemodynamics remained stable, the patient was extubated in the intensive care unit 2 h after surgery, and postoperative recovery was uneventful. This case demonstrates that well-selected very elderly patients may successfully undergo complex oncologic surgery when care is individualized, multidisciplinary collaboration is strong, and modern perioperative strategies are rigorously applied.

Indexed as

Aortic stenosisElderlyEnhanced recovery after surgeryFrailtyMajor surgeryTotal intravenous anesthesia

Identifiers

PMID41953872
PMCPMC13053470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.