Evidence map›Paper›PMID 41953723›Full record

ArticleMaterials today. Bio2026

Targeted antibacterial and mesenchymal stem cell-modulatory hydrogel for periodontitis treatment.

Shuhan Li, Xiang Chen, Haonan Zhao, Rui Ma, Yuxiao Wang, Guichun Wang, Kaili Zhang, Xuyang Xia, Xiaodong Ma, Bo Wu and 7 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shuhan LiCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Xiang ChenCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Haonan ZhaoCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Rui MaCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Yuxiao WangCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Guichun WangCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Kaili ZhangCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Xuyang XiaCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Xiaodong MaCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Bo WuCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Yuzhe HuangCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Zixuan ShuCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Jian GuoCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Yaotian TaoCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Shuangying GuiCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Yang DingCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Chengjun PengCollege of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical debridement and systemic antibiotics, as current therapeutic modalities for periodontitis, suffer from limitations, including insufficient local efficacy and bacterial resistance. Herein, a dual-mode injectable hydrogel (A-CC-PBA@ZIF-8@CAPE Gel) has been designed and prepared for enhancing the therapeutic efficacy through targeted anti-infection and rectification of the dysregulated mitochondrial function of mesenchymal stem cells (MSCs) in inflammatory state. Both the

Indexed as

Bifunctional hydrogelsMesenchymal stem cellsMitochondrial dysfunctionPeriodontitisTargeted antibacterial

Identifiers

PMID41953723
PMCPMC13053792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.