ArticleFrontiers in cardiovascular medicine2026
Impaired sensitivity to thyroid hormones is associated with atrial fibrillation in the euthyroid population.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The relationship between thyroid hormone sensitivity and atrial fibrillation (AF) progression remains unclear. Objective: This study aimed to investigate the relationship between impaired thyroid hormone sensitivity and the progression of AF in individuals with normal thyroid function. Methods: This retrospective cross-sectional study included 1,190 consecutive patients with AF, who were classified into paroxysmal AF ( Results: Compared with the paroxysmal AF group, patients with persistent AF exhibited significantly higher PTFQI and TT4RI values and a lower FT3/FT4 ratio ( Conclusion: Impaired thyroid hormone sensitivity may contribute to the progression from paroxysmal to persistent AF in euthyroid patients; however, its clinical predictive value requires further validation in large-scale studies.
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