Evidence map›Paper›PMID 41953662›Full record

ArticleFrontiers in cardiovascular medicine2026

Sex differences in LMR ratio and coronary artery stenosis severity among patients with coronary artery disease.

Cheng Cao, Wenyi Pang, Lingling Lu, Yang Zhao, Lu Lu, Hongmin Zhao

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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Cheng CaoCardiology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.
Wenyi PangCardiology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.
Lingling LuCardiology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.
Yang ZhaoOncology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.
Lu LuCardiology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.
Hongmin ZhaoCardiology Department, Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine of Hebei, Cangzhou, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have indicated that the lymphocyte-to-monocyte ratio (LMR) is associated with the severity of coronary artery disease (CAD). However, whether this association differs between sexes remains unclear. This study aimed to evaluate the association between LMR and Gensini score in patients with CAD, with a focus on potential sex differences. Methods: A total of 1,673 patients undergoing coronary angiography were included. The severity of CAD was assessed using the Gensini score, and patients were categorized into three groups based on Gensini score tertiles: T1 (≤10), T2 (>10 to <44), and T3 (≥44). Sex-stratified analyses and multivariable regression models were employed to assess the association between LMR and CAD severity. Results: LMR was significantly lower in patients with higher Gensini scores ( Conclusion: LMR is independently and inversely associated with the severity of CAD, with a stronger association observed in female patients. These findings suggest that LMR may serve as a potential inflammatory marker for assessing CAD severity, and its clinical relevance may differ between sexes.

Indexed as

coronary artery diseasecoronary artery stenosis severitygensini scorelymphocyte-to-monocyte ratiosex differences

Identifiers

PMID41953662
PMCPMC13055545

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