ArticleFrontiers in nutrition2026
Comparative associations of three nutritional indices with hematoma expansion after intracerebral hemorrhage.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hematoma expansion (HE) is a major determinant of early neurological deterioration after intracerebral hemorrhage (ICH) and remains a key target for early risk assessment. Nutritional indices obtained at hospital admission can reflect acute physiological vulnerability during hemorrhagic injury, but their relative relevance to HE has not been well established. This study investigated the associations between three commonly used nutritional indices and HE in patients with ICH. Methods: We retrospectively included patients with ICH admitted between January 2023 and December 2024. Nutritional status at admission was assessed using the Prognostic Nutritional Index (PNI), the Triglycerides × Total Cholesterol × Body Weight Index (TCBI), and the Controlling Nutritional Status (CONUT) score. HE was defined as a relative hematoma growth >33% or an absolute increase >6 mL on follow-up computed tomography. Associations between each nutritional index and HE were examined using univariable and multivariable logistic regression. Restricted cubic spline (RCS) analysis was used to characterize the association pattern, and subgroup and sensitivity analyses were performed to evaluate consistency of the findings. Results: Among 349 included patients, 42 (12.0%) developed HE. Higher CONUT scores were significantly associated with an increased risk of HE (OR = 1.29, 95%CI: 1.03-1.59, Conclusion: This study demonstrated a significant association between nutritional status and HE in ICH. Among the nutritional indices examined, CONUT showed a positive association, suggesting its role as a practical nutritional risk indicator for early risk stratification of HE in ICH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.