ArticleGynecologic oncology reports2026
Müllerian adenosarcoma in a young adult: A case report and literature review of diagnostic and management challenges.
Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Müllerian adenosarcoma is a rare biphasic uterine malignancy typically affecting postmenopausal women. Its occurrence in young, nulliparous women is extremely uncommon, presenting diagnostic challenges, especially in cases of presumed recurrences. Case Presentation: A 22-year-old nulliparous woman presented with a presumed recurrent, enlarging prolapsing uterine mass and post-coital bleeding. Her history was notable for two prior excisions of a similar mass without histopathological review. Examination revealed a 6 cm friable mass protruding through the cervical os. Given the recurrence and risk of hemorrhage in a resource-limited setting, a total abdominal hysterectomy was performed. Gross examination identified a 9x6x4 cm polypoid mass confined to the fundus. Histopathology confirmed high-grade endometrial adenosarcoma, characterized by classic biphasic features, significant spindle-cell atypia, and a brisk mitotic rate (>10 mitoses/10 HPFs). Immunohistochemistry showed stromal positivity for CD10 and PR. No myometrial invasion or lymphovascular space invasion was observed. The patient remains asymptomatic under a rigorous three-month surveillance protocol. Conclusion: This case highlights a rare high-grade presentation in a young adult. Despite aggressive histological features, the absence of myometrial invasion supports definitive surgery followed by intensive long-term surveillance. This report underscores the necessity of a high index of suspicion for malignancy in recurrent polypoid masses within the reproductive age group and addresses critical gaps regarding fertility preservation and age-specific management protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.