Evidence map›Paper›PMID 41953456›Full record

ArticleFrontiers in bioinformatics2026

Human-associated NDM-5-producing multidrug-resistant

Mirena Ivanova, Joana Mourão, Judit Szarvas, Elif S Tosun, Niamh Lacy-Roberts, Natasia Rebekka Thornval, Zita Záborcki, Szilárd Jánosi, Raquel Garcia-Fierro, Pierre-Alexandre Beloeil and 4 more

Erratum issuedAbstract read
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In one paragraph

Article in Frontiers in bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Mirena IvanovaEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Joana MourãoEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Judit SzarvasThe Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Elif S TosunEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Niamh Lacy-RobertsEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Natasia Rebekka ThornvalEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Zita ZáborckiNational Food Chain Safety Office, Veterinary Diagnostic Directorate, Budapest, Hungary.
Szilárd JánosiNational Food Chain Safety Office, Veterinary Diagnostic Directorate, Budapest, Hungary.
Raquel Garcia-FierroEuropean Food Safety Authority, Parma, Italy.
Pierre-Alexandre BeloeilEuropean Food Safety Authority, Parma, Italy.
Ernesto LiebanaEuropean Food Safety Authority, Parma, Italy.
Beatriz GuerraEuropean Food Safety Authority, Parma, Italy.
Rene S HendriksenEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.
Jette S KjeldgaardEuropean Union Reference Laboratory for Antimicrobial Resistance (EURL-AR), Research Group for Global Capacity Building, Technical University of Denmark, Kongens Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbapenem-resistant Enterobacterales pose a significant public health threat, particularly when detected in food-producing animals and retail meat. Although carbapenems are not used in European Union animal production, sporadic cases of carbapenemase-producing Methods: In this study, we characterize three multidrug-resistant (MDR) Results: All three isolates belonged to the human-associated uropathogenic clone ST405 (O102:H6) and were clonally related with a maximum of two single nucleotide polymorphisms. They exhibited identical genomic profiles conferring resistance to carbapenems, cephalosporins, fluoroquinolones, tetracycline, and azithromycin. Comparative genomic analysis revealed close genetic relationships with human clinical isolates from Australia and the United Kingdom, suggesting international dissemination. The Conclusion: The detection of human-associated

Indexed as

blaNDM-5carbapenemase-producing EnterobacteralesEscherichia coli ST405horizontal gene transferIncFII-IncFIB plasmidmultidrug resistanceone health surveillance

Identifiers

PMID41953456
PMCPMC13053247

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.