Evidence map›Paper›PMID 41953450›Full record

ArticleCurrent addiction reports2026

The Association of Emotion Dysregulation with the Co-Occurrence of PTSD and SUD: A Systematic Review of Recent Literature.

Eileen Barden, Craig Polizzi, Robyn Ellis, Cathryn Glanton Holzhauer

Abstract read
In one paragraph

Article in Current addiction reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eileen BardenVA Boston Healthcare System, Boston, USA.
Craig PolizziVA Boston Healthcare System, Boston, USA.
Robyn EllisDivision of Alcohol, Drugs & Addiction, McLean Hospital, Belmont, USA.
Cathryn Glanton HolzhauerDepartment of Psychiatry, University of Connecticut, Farmington, USA.

Funding

Pilot StudiesP50AA027055 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HOLZHAUER, CATHRYN GLANTON, STEFFENS, DAVID C. · 2019 to 2023
$7.8M
Postdoctoral Training Program in Stress and TraumaT32MH019836 · NIMH · TUFTS UNIVERSITY BOSTON · PI DENISE M. SLOAN · 1996 to 2026
$4.7M
NIAAA NIH HHS P50 AA027055NIMH NIH HHS T32 MH019836
6 · The paper itself

Abstract

Purpose of Review: This review focused on literature from the past five years that examined the role of emotion dysregulation in co-occurring symptoms of posttraumatic stress disorder (PTSD) and substance use disorder (SUD) among adults. Recent Findings: Evidence from recent studies indicates that emotion dysregulation operates directly by exacerbating symptoms of PTSD and SUD and functions as both a moderator and mediator in the PTSD-SUD relation. Greater emotion dysregulation tends to strengthen the association between PTSD and SUD symptoms. Moreover, evidence supports emotion dysregulation as a key target in trauma- and SUD-focused treatments, with reductions in emotion dysregulation contributing to better clinical outcomes across diverse treatment settings. Summary: Emotion dysregulation is a critical factor that underlies the co-occurrence of PTSD and SUD. Understanding the nuanced role of emotion dysregulation in co-occurring PTSD-SUD offers critical insights for alleviating PTSD symptoms and SUD behaviors, especially intrusive memories and using substances as avoidance.

Indexed as

Emotion dysregulationPTSDReviewSubstance useTrauma

Identifiers

PMID41953450
PMCPMC13056375

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.