Evidence map›Paper›PMID 41953375›Full record

ArticleInternational journal of breast cancer2026

Thymoquinone Enhances Tamoxifen Efficacy Against Triple-Negative Breast Cancer by Targeting EMT Signaling.

Mazharul Haque, Ritis K Shyanti, Sudhanshu Sharma, Hongzhuan Wu, Manoj K Mishra

Abstract read
In one paragraph

Article in International journal of breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mazharul HaqueCancer Research Center, Biological Sciences, Alabama State University, Montgomery, Alabama, USA, alasu.edu.ORCID https://orcid.org/0009-0009-8758-5075
Ritis K ShyantiCancer Research Center, Biological Sciences, Alabama State University, Montgomery, Alabama, USA, alasu.edu.ORCID https://orcid.org/0000-0002-2930-6332
Sudhanshu SharmaCancer Research Center, Biological Sciences, Alabama State University, Montgomery, Alabama, USA, alasu.edu.
Hongzhuan WuCancer Research Center, Biological Sciences, Alabama State University, Montgomery, Alabama, USA, alasu.edu.ORCID https://orcid.org/0009-0004-3232-3485
Manoj K MishraCancer Research Center, Biological Sciences, Alabama State University, Montgomery, Alabama, USA, alasu.edu.ORCID https://orcid.org/0000-0001-7563-6474

Funding

Intersection of Social Capital, Mentorship and Networking on Persistence, Engagement and Science IdentityU01GM132769 · NIGMS · ALABAMA STATE UNIVERSITY · PI MISHRA, MANOJ K. · 2019 to 2023
$3.0M
Alabama State University-Auburn University Partnership to Promote Diversity in Aging ResearchR25AG070244 · NIA · ALABAMA STATE UNIVERSITY · PI MISHRA, MANOJ K., SUPPIRAMANIAM, VISHNU D · 2022 to 2024
$876k
NIA NIH HHS R25 AG070244NIGMS NIH HHS U01 GM132769
6 · The paper itself

Abstract

The variety of available therapies for treating TNBC is constrained by the minimal or no expression of receptors such as estrogen (ER), progesterone (PR), and human epidermal growth factor 2 (HER2). However, estrogen receptor

Indexed as

combinatorial therapydocking and simulationepithelial–mesenchymal transitiontamoxifenthymoquinonetriple-negative breast cancer

Identifiers

PMID41953375
PMCPMC13053650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.