ReviewJournal of toxicology2026
Microplastics Induced Dysfunctions in Physiology and Behavior of Fish: A Comprehensive Review.
Review in Journal of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Microplastics Induced Dysfunctions in Physiology and Behavior of Fish: A Comprehensive Review.Journal of toxicology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics (MPs) pollution is a global concern due to their widespread persistence, occurrence, and toxicity to aquatic organisms. Fish are most vulnerable to MPs due to their feeding habits and ecological niches. This review critically synthesizes current evidences on MPs induced disruptions of key physiological functions and behavioral patterns in fish, with an emphasis on the underlying mechanistic pathways and biological consequences. MPs originate from various sources, entering aquatic systems and being ingested by fish directly or via trophic transfer. A prominent effect is growth inhibition commonly caused by gastrointestinal damage, impaired nutrient absorption, and metabolic stress. Moreover, it causes several hematobiochemical disruptions including anemia, leukocyte fluctuations, and biochemical and enzymatic imbalances that are connected to oxidative stress and immunosuppression. MPs also disrupt reproductive performances of fish through altering gonadosomatic index, inducing endocrine disruptions, dysregulating hypothalamic-pituitary-gonadal axis genes, and reducing fertilization and hatching success, with several transgenerational effects. Furthermore, MPs can induce oxidative stress through overproduction of reactive oxygen species (ROS) and modulation of antioxidant enzymes, along with dysregulation of immune and inflammatory responses. Behavioral alterations include reduced swimming performance and changes in feeding and reproductive behavior, which are linked to neurotoxicity and impairment of energy metabolism. Although a limited number of studies suggest species-specific effects, most studies highlight significant adverse impacts on fish health. Hence, this review and meta-analysis indicates that MPs substantially compromise fish physiology manifesting as poor growth, altered blood and metabolic profiles, impaired reproduction, and behavioral patterns. By integrating sources and transport pathways to physiological and behavioral outcomes, this review provides a comprehensive summary to inform ecological risk assessment and management of MPs in fisheries and aquatic ecosystems.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.