Evidence map›Paper›PMID 41953240›Full record

ArticleQatar medical journal2025

Serious adverse effect of low-dose dexmedetomidine under spinal anesthesia: A case report and literature review.

Muhammad Firas Alhammad, Muhammad Jaffar Khan, Arunabha Karmakar, Hazim Kassas, Yasser Hammad, Yasir Ahmed, Mohamad Talal Basrak, Tarek Tageldin, Adnan Alshami, Nabil Shallik

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Qatar medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad Firas AlhammadAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Muhammad Jaffar KhanAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Arunabha KarmakarAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Hazim KassasAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Yasser HammadAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Yasir AhmedAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Mohamad Talal BasrakTower Health, West Reading, Pennsylvania, United States of America.
Tarek TageldinAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.
Adnan AlshamiDepartment of Anesthesia, Intensive and Emergency Medicine, and Pain Management, Helios Klinikum Cuxhaven, Lower Saxony, Germany.
Nabil ShallikAnaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dexmedetomidine is a highly selective α Conclusion: We opine that the use of dexmedetomidine as a sedative agent in patients under spinal anesthesia requires heightened caution due to the risk of major adverse cardiac events. Our case exemplifies that this risk persists even in healthy young patients, at low drug infusion rates, and even after avoiding a loading dose.

Indexed as

bradycardiaDexmedetomidineneuraxial anesthesiapericardiac arrestspinal anesthesia

Identifiers

PMID41953240
PMCPMC13014107

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.