Evidence map›Paper›PMID 41953228›Full record

ArticleNeurosurgical focus: Video2026

Hybrid approach to closure in fetoscopic myelomeningocele repair.

Natasha Hongsermeier-Graves, Vance R Mortimer, Stephen J Fenton, Martha A Monson, Robert J Bollo

Abstract read
In one paragraph

Article in Neurosurgical focus: Video, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natasha Hongsermeier-GravesDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City.
Vance R MortimerDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City.
Stephen J FentonDepartment of Surgery, Division of Pediatric Surgery, University of Utah School of Medicine and Primary Children's Hospital, Salt Lake City.
Martha A MonsonDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Utah, Salt Lake City; and.
Robert J BolloDepartment of Neurosurgery, Division of Pediatric Neurosurgery, University of Utah School of Medicine and Primary Children's Hospital, Salt Lake City, Utah.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural tube defects (NTDs) affect 2 in 1000 births worldwide. Myelomeningocele (MMC) represents a severe NTD, often with permanent neurological sequelae. The randomized multicenter Management of Myelomeningocele Study (MOMS) showed that open prenatal (compared to postnatal) myelomeningocele closure could reverse hindbrain herniation, lower rates of shunt insertion for hydrocephalus, and improve neurological function, with the trade-off of increased maternal complications and premature birth. Fetoscopic approaches may have equivalent benefits to open fetal MMC closure with fewer maternal complications. The hybrid approach to fetoscopic repair (primary closure vs biosubstitute patch) described in this video can be tailored to individual fetal anatomy and promote comparable epithelialization over time. The video can be found here: https://stream.cadmore.media/r10.3171/2026.1.FOCVID25222.

Indexed as

fetal surgeryfetoscopicmyelomeningocelemyeloschisisneural tube defectspina bifida

Identifiers

PMID41953228
PMCPMC13055898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.