Evidence map›Paper›PMID 41953225›Full record

ArticleNeurosurgical focus: Video2026

Fetoscopic repair of myeloschisis: optimizing the three-layer closure.

Matthieu D Weber, Ryan B Juncker, Eric A Sribnick, Karen A Diefenbach, Adolfo Etchegaray, Jeffrey R Leonard, Oluseyi K Ogunleye, Jonathan A Pindrik, Oluyinka O Olutoye, Albert M Isaacs

Abstract read
In one paragraph

Article in Neurosurgical focus: Video, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthieu D WeberCollege of Medicine, The Ohio State University, Columbus.
Ryan B JunckerCollege of Medicine, The Ohio State University, Columbus.
Eric A SribnickDepartment of Neurological Surgery, The Ohio State University, Columbus.
Karen A DiefenbachDepartment of Pediatric Surgery, Nationwide Children's Hospital, Columbus.
Adolfo EtchegarayDivision of Fetal Medicine, Nationwide Children's Hospital, Columbus; and.
Jeffrey R LeonardDepartment of Neurological Surgery, The Ohio State University, Columbus.
Oluseyi K OgunleyeDivision of Fetal Medicine, Nationwide Children's Hospital, Columbus; and.
Jonathan A PindrikDepartment of Neurological Surgery, The Ohio State University, Columbus.
Oluyinka O OlutoyeDepartment of Pediatric Surgery, Nationwide Children's Hospital, Columbus.
Albert M IsaacsDepartment of Neurological Surgery, The Ohio State University, Columbus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 25-year-old female presented at 24 weeks and 2 days of gestation with suspected myeloschisis on fetal anatomical survey. Imaging demonstrated an L4-S4 defect, ventriculomegaly, and Chiari type II malformation. Closure remains one of the least standardized components of fetoscopic repair, although small studies have suggested that three-layer repair may reduce CSF leakage, shorten maternal hospitalization, decrease revision rates, and improve Chiari malformation outcomes. The patient underwent a three-port fetoscopic repair with three-layer closure. The authors showcase their approach and advocate for closure technique standardization and its correlation with long-term neurological outcomes in the post-Management of Myelomeningocele Study (MOMS) trial era. The video can be found here: https://stream.cadmore.media/r10.3171/2026.1.FOCVID25217.

Indexed as

fetal surgeryfetoscopymultilayermyeloschisisneurosurgerypediatricrepairspina bifida

Identifiers

PMID41953225
PMCPMC13055902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.