Evidence map›Paper›PMID 41953140›Full record

ArticleJournal of tissue engineering

Engineering a skeletal muscle model to study extracellular vesicle dynamics.

María Fernández-Rhodes, Rowan Rimington, Jacob Fleming, Andrew J Capel, Owen G Davies, Mark P Lewis

Abstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Fernández-RhodesSchool of Sports Exercise and Health Sciences, Loughborough University, UK.
Rowan RimingtonSchool of Sports Exercise and Health Sciences, Loughborough University, UK.
Jacob FlemingSchool of Sports Exercise and Health Sciences, Loughborough University, UK.
Andrew J CapelSchool of Sports Exercise and Health Sciences, Loughborough University, UK.
Owen G DaviesSchool of Sports Exercise and Health Sciences, Loughborough University, UK.ORCID https://orcid.org/0000-0003-0808-8695
Mark P LewisSchool of Sports Exercise and Health Sciences, Loughborough University, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle (SM) functions both mechanically and as a secretory organ, releasing myokines and extracellular vesicles (EVs) involved in myogenic regulation and inter-tissue communication. While 3D bioengineered SM models are widely used for studying muscle physiology, few have been applied to investigate EV dynamics. This study optimised a 3D SM model to support mature myotube formation and evaluated its utility for SM-EV analysis. Myosin heavy chain expression was reduced at higher Matrigel

Indexed as

3D cultureextracellular vesiclesmodelmyoblastskeletal muscletissue engineering

Identifiers

PMID41953140
PMCPMC13053972

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.