ArticleiScience2026
Evidence of persistent hunger following dietary weight loss in mice.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Over 40% of adults in the United States struggle with obesity, and nearly half have attempted weight loss, yet most efforts result in weight regain. Rodent models have been used to study the physiological drivers of this phenomenon, but it remains unclear whether they exhibit weight regain after sustained weight loss. To address this, we developed a mouse model of reversed dietary obesity (ReDO) that demonstrates susceptibility to weight regain following sustained weight loss. Male diet-induced obese (DIO) mice were calorically restricted (CR) until weight-matched to controls, then pair-fed for 0, 8, or 28 days, or chronically. Upon return to
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.