Evidence map›Paper›PMID 41952992›Full record

ArticleiScience2026

Reconstruction of the genetic history of the Austro-Asiatic- and Dravidian-speaking tribal populations of South Asia.

Arghya Dey, Manisha Pal, Diptarup Nandi, Analabha Basu

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Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Arghya DeyBiotechnology Research Innovation Council-National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Manisha PalDepartment of Statistics, Faculty of Science, St. Xavier's University, Kolkata, West Bengal, India.
Diptarup NandiSchool of Arts and Sciences, Azim Premji University, Bengaluru, Karnataka 562125, India.
Analabha BasuBiotechnology Research Innovation Council-National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ancestors of Austro-Asiatic- and Dravidian-speaking tribal populations are among the earliest settlers of South and Southeast Asia (S&SEA). While Austro-Asiatic speakers are distributed across S&SEA, Dravidian speakers are primarily confined to South India. Previous studies have identified the Indian Austro-Asiatic and Dravidian tribal populations to maximally represent two distinct genetic ancestral components, ancestral Austro-Asiatic (AAA) and ancestral South Indian (ASI), respectively. Leveraging the whole genome sequence (WGS) dataset from GenomeAsia 100K project, we investigated the genetic relationship of the tribal populations within the broader South Asian demographic landscape. Our analyses reveal that AAA and ASI components diverged ∼15,000-20,000 years before present (ybp), shortly after Last Glacial Maximum-a period marked by ecological shifts and regional isolation. This divergence postdates the separation (∼20,000-30,000 ybp) between the Indian (AAA) and Southeast Asian (AAM) Austro-Asiatic ancestries, indicating a deep and widespread pre-Neolithic distribution of this ancestral population across S&SEA. Additionally, recent (∼750-1500 ybp) gene flow between Central Indian Dravidian and Austro-Asiatic tribes produced notable genetic-linguistic discordances.

Indexed as

Biological sciencesHuman genetics

Identifiers

PMID41952992
PMCPMC13053704

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