Evidence map›Paper›PMID 41952986›Full record

ArticleiScience2026

Passive OPM-MEG paradigm reveals altered brain network organization in children with DLD.

Aimin Liang, Zhijun Cui, Jialing Wang, Hanxiao Wang, Yang Shi, Chunyan Qu, Jinbiao Liu, Xin Ni, Xiaolin Ning, Jiancheng Fang

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In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Aimin LiangSchool of Instrumentation Science and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Zhijun CuiChildren's Health Care Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Jialing WangHangzhou Lingci Medical Equipment Co., Ltd, Hangzhou 310051, China.
Hanxiao WangChildren's Health Care Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Yang ShiChildren's Health Care Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Chunyan QuChildren's Health Care Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Jinbiao LiuHangzhou Institute of Extremely-Weak Magnetic Field Major National Science and Technology Infrastructure, Hangzhou 310051, China.
Xin NiBeijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.
Xiaolin NingSchool of Instrumentation Science and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Jiancheng FangSchool of Instrumentation Science and Optoelectronic Engineering, Beihang University, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optically pumped magnetometer magnetoencephalography (OPM-MEG) enables the study of pediatric neurodevelopment during naturalistic tasks. Here, we investigated functional connectivity (FC) changes in 30 typically developing (TD) children and 10 children with developmental language disorder (DLD), aged 4-7 years, during a rest task ("Inscapes" video) and a story task (short narrative videos). Both groups exhibited similar power modulation (δ enhancement, α, β, and low-γ suppression) and decreased network modularity when transitioning from rest to story processing. However, children with DLD displayed increased high-γ network modularity, indicating a more segregated neural architecture. During the story task, TD children displayed enhanced low-γ FC within a left-hemisphere network with hubs in temporal, parietal, central, and occipital regions, whereas children with DLD showed weaker connectivity. These findings suggest that altered γ-band network organization may be a core neural signature of DLD and highlight the potential of OPM-MEG in pediatric neurodevelopmental disorders.

Indexed as

Health sciencesInternal medicineMedical specialtyMedicineNeurology

Identifiers

PMID41952986
PMCPMC13053697

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.