SynthesisFrontiers in medicine2026
Association between ultra-processed food consumption and risk of irritable bowel syndrome and functional dyspepsia: a systematic review and meta-analysis of observational studies.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ultra-processed foods (UPFs) are increasingly prevalent in global diets and have been linked to various adverse health outcomes. However, evidence regarding their association with disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS) and functional dyspepsia (FD), remains inconsistent. Objective: To systematically evaluate the association between UPFs consumption and the risk of IBS and FD through a comprehensive meta-analysis of observational studies. Methods: We conducted a systematic search of PubMed, Embase, Cochrane Library, and Web of Science from inception through December 2025. Observational studies assessing UPFs intake and clinically diagnosed IBS or FD in adults were included. Pooled effect estimates [odds ratios (OR)] were calculated using random-effects models. Heterogeneity was assessed with Results: Ten studies ( Conclusion: These findings suggest that reducing UPFs intake may be a promising dietary strategy for IBS prevention and management. For FD, the evidence is preliminary and requires confirmation in larger prospective studies. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420251269914, identifier PROSPERO (CRD420251269914).
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Registered trials
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