ArticleInternational journal of reproductive biomedicine2026
The effects of different doses of Stanozolol on sperm parameters and testicular histology in male rats: An experimental study.
Article in International journal of reproductive biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stanozolol, an anabolic steroid, has potential therapeutic applications but is also linked to numerous adverse health effects. Objective: This study aimed to assess the effects of different doses of Stanozolol on testicular tissue and sperm quality in rats. Materials and Methods: This experimental study was conducted at the Department of Biology, College of Education for Pure Sciences, University of Karbala, Karbala, Iraq, between September and November 2022. In this study, 20 male Wistar rats (8-10 wk old, 250-325 gr) were randomly divided into 4 groups (n = 5/group). The control group was orally gavaged with distilled water. Groups 2, 3, and 4 were administered Stanozolol at doses of 5, 10, and 15 mg/kg by gavage daily. After 60 days, the animals were sacrificed. The testes and epididymis were then removed, weighed, and prepared for histological examination and sperm parameter analysis. Results: Compared to the control group, all groups that received Stanozolol showed a statistically significant decrease (p Conclusion: The present study concludes that the use of different doses of Stanozolol induces serious adverse effects on reproductive health, particularly on testicular tissue and sperm quality.
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