Evidence map›Paper›PMID 41952737›Full record

ReviewSurgical neurology international2026

Barriers to care to pediatric brain tumors in low- and middle-income countries: A proposal for a critical framework.

Savi Agarwal, Jorge Lazareff

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Savi AgarwalDavid Geffen School of Medicine, University of California Los Angeles, CA, United States.
Jorge LazareffDepartment of Neurosurgery, David Geffen School of Medicine at UCLA, Center for Health Sciences, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric brain tumors (PBTs) represent the most prevalent solid cancers among children. Eighty percentages of those patients live in low- and middle-income countries (LMIC). There is a robust body of literature exploring the barriers to care (BTCs) to surgical pathologies in LMIC that include directly or indirectly PBT. All authors agree that systemic barriers worsen PBT care in LMIC. We aim to determine which are the three most frequently identified BTCs in the 2010-2025 literature, define a common conceptual problem to all of them, and propose an alternative framework. Methods: A narrative review on BTCs to PBT in LMIC across MEDLINE, PubMed Central, Cochrane Library, Google Scholar, and Embase was performed for English-language publications from 2010 and 2025. Results: We identified 122 papers relevant to our work. The most common BTCs can be grouped as (1) delayed diagnosis and referral due to misidentification of symptoms, limited diagnostic tools, and lack of national databases, (2) scarcity of neurosurgical personnel and adequate equipment for treatment, and (3) lack of formal pediatric neuro-oncology programs or infrastructure to guide both physicians and families. All of the above indicate that the problem of BTCs in LMICs is a structural problem related to national public health policies. Conclusion: The most efficient solution to BTCs to PBT stems from a change of national health policy.

Indexed as

Barriers to careCost-effectivenessPediatric brain tumorsState security

Identifiers

PMID41952737
PMCPMC13054315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.