ArticleTransfusion2026
Perceptions of blood volume and iron recovery following a whole-blood or plasma donation: A cross-sectional study with donors and non-donors.
Article in Transfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
backgroundPerceptions of how blood or plasma donation affect the body and recovery experiences drive subsequent donation behavior. This paper aims to describe (1) how donors typically feel after a donation, (2) how long donors and non-donors believe their bodies need to recover from volume and iron loss, and (3) what activities donors undertake to recover following a whole-blood (WB) or plasma donation. STUDY DESIGN AND
methodsA survey on blood donation recovery was distributed to WB and plasma donors via email, and to non-donors online. Comparative analyses (donor type, gender, and age group) were conducted.
resultsThe survey was completed by 632 WB donors, 601 plasma donors, and 294 non-donors. Most donors (54%) reported feeling no different after their donation, with similar experiences reported by WB and plasma donors. Women and younger donors reported feeling more tired than men and older donors. Two-thirds believed blood volume recovery occurs within 24 h, with non-donors estimating longer recovery times. For iron, most (72%) respondents believed their bodies recover within a week, with WB donors and younger donors believing it takes longer. Regarding post-donation advice, most donors report drinking extra water (75%) and avoiding strenuous exercise (62%), with fewer donors eating iron-rich foods (16%) or taking iron tablets (6%). DISCUSSION: Some donors and non-donors over or underestimate post-donation recovery times. These findings highlight the need for targeted education to improve donor understanding of physiological recovery and promote evidence-based recovery strategies.
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