ArticleJournal of the American Geriatrics Society2026
Primary Care Practitioners' Approaches to Deprescribing Opioids for Older Adults With Chronic Pain: A Qualitative Analysis.
Article in Journal of the American Geriatrics Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundRisks related to long-term opioid therapy for chronic pain are high and may increase over time with aging. Deprescribing may be a beneficial intervention for older adults prescribed chronic opioids.
methodsSemi-structured interviews with hypothetical clinical cases of older adults prescribed opioids for chronic pain: (1) low-risk case: a patient prescribed low-dose opioids without concerns; (2) moderate-risk case: a patient with multimorbidity and concurrent benzodiazepine use prescribed moderate opioid doses; (3) high-risk case: a patient prescribed high-dose opioids with signs of an opioid use disorder (OUD). PCPs were asked, in an open-ended fashion, to discuss whether they would initiate a deprescribing conversation, how they would approach deprescribing, and how they would approach a patient who declined recommendations to deprescribe. PARTICIPANTS AND
settingPCPs from a Massachusetts health system.
results18 PCPs participated (56% female, 78% academic). More than half of PCPs would initiate a deprescribing conversation across the three cases. PCPs' approach to deprescribing and mitigating risks differed based on clinical risk. In low and moderate-risk cases, PCPs emphasized a patient-directed taper plan and education on opioid risks. In the high-risk case, some PCPs were uncertain about initiating a deprescribing conversation due to concerns about the patient's mental health and the risk of illicit opioid use. Naloxone was infrequently recommended across the three cases, but in the high-risk case, approximately half of PCPs suggested medications for OUD.
conclusionsPCPs reported that they would often initiate opioid deprescribing conversations with older adults, but were less confident in managing older adults with signs of OUD. PCPs require additional support to implement successful conversations on opioid deprescribing with older adults.
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