Evidence map›Paper›PMID 41952233›Full record

ArticleJournal of cardiothoracic surgery2026

Video-Assisted Thoracoscopic Surgery Versus Thoracotomy for Pleural Empyema: Outcomes and Risk Factors in a Retrospective Single-Center Cohort Study.

Josef Yayan, Amr Khalil, Marcus Krüger, Christian Biancosino

Abstract readComparative Study
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Josef YayanDepartment of Internal Medicine, Division of Pulmonary, Allergy, and Sleep Medicine, HELIOS Clinic Wuppertal, Witten/Herdecke University, Heusnerstr. 40, Wuppertal, 42283, Germany. josef.yayan@hotmail.com.
Amr KhalilDepartment of Thoracic Surgery, HELIOS Clinic Wuppertal, Witten/Herdecke University, Wuppertal, Germany.
Marcus KrügerDepartment of Thoracic Surgery, Martha-Maria Hospital Halle-Dölau, Halle, Germany.
Christian BiancosinoDepartment of Thoracic Surgery, HELIOS Clinic Wuppertal, Witten/Herdecke University, Wuppertal, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPleural empyema is a serious complication of pulmonary infections that often requires surgical intervention . This study compared outcomes between video-assisted thoracoscopic Surgery (VATS) and thoracotomy, with particular attention to postoperative complications, intensive care unit (ICU) admission rates, and intraoperative parameters. The aim was to evaluate associations between surgical approach and perioperative outcomes in routine clinical practice.

methodsWe retrospectively reviewed 103 patients who underwent surgical management for pleural empyema at a university thoracic surgery department between December 2019 and May 2024. Nineteen patients (18.4%) underwent VATS, and 84 patients (81.6%) underwent thoracotomy. The surgical approach was determined based on disease stage and intraoperative surgical assessment. Primary outcomes included postoperative complications and ICU admissions, while secondary outcomes included transfusion requirements and operative duration. Ethical approval was obtained prior to study initiation.

resultsComplications occurred significantly less frequently following VATS than after thoracotomy (10.5% vs. 51.2%, p = 0.005). ICU admissions were also less common in the VATS group (57.9% vs. 86.9%, p = 0.005). No patients in the VATS group required transfusions, whereas 28.6% patients in the thoracotomy group did (p = 0.057). Operative time did not differ significantly between the groups (VATS: 99.6 min; thoracotomy: 116.4 min, p = 0.181). Intraoperative pathogen detection rates were similar (OR 0.88, 95% CI: 0.301–2.544, p = 0.807).

conclusionsIn this retrospective cohort, VATS was associated with lower rates of postoperative complications and ICU admissions compared with thoracotomy in appropriately selected patients. Thoracotomy remains essential indispensable in advanced disease requiring extensive decortication, likely reflecting underlying disease severity rather than the surgical approach itself . Given the retrospective design and imbalance in group sizes , these findings should be interpreted with caution. Prospective multicenter studies are needed to confirm these findings and refine surgical decision-making criteria.

Indexed as

Empyema, PleuralThoracic Surgery, Video-AssistedThoracotomyAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk FactorsTreatment OutcomePleural empyemaPostoperative complicationsSurgical outcomesThoracotomyVideo-assisted thoracoscopic surgery (VATS)

Identifiers

PMID41952233
PMCPMC13085428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.