Evidence map›Paper›PMID 41951855›Full record

ArticleCell research2026

GSK3α functions as a stemness checkpoint across multiple stem cell states.

Duo Wang, Xiukun Wang, Safia Malki, Yanpui Chan, Brian Bennett, Joshua Feng, Jiaqi Tang, Xi Chen, Daniel McKim, Chao Zhang and 5 more

Abstract readLetter
In one paragraph

Article in Cell research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Duo Wang *Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. wangduotc@gmail.com.ORCID http://orcid.org/0009-0001-5060-8968
Xiukun Wang *Epigenetics and RNA Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA.
Safia MalkiEpigenetics and RNA Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA.
Yanpui ChanEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Brian BennettEpigenetics and RNA Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA.
Joshua FengLoker Hydrocarbon Research Institute & Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
Jiaqi TangLoker Hydrocarbon Research Institute & Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
Xi ChenEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0009-0007-4625-7441
Daniel McKimEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Chao ZhangLoker Hydrocarbon Research Institute & Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
Litao TaoDepartment of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE, USA.
Jie XuCenter for Advanced Models Translational Sciences and Therapeutics, University of Michigan Medical School, Ann Arbor, MI, USA.
Y Eugene ChenCenter for Advanced Models Translational Sciences and Therapeutics, University of Michigan Medical School, Ann Arbor, MI, USA.
Guang HuEpigenetics and RNA Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, USA. guang.hu@nih.gov.
Qi-Long YingEli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. qying@med.usc.edu.ORCID http://orcid.org/0000-0001-5822-9498

Funding

Chicken embryonic stem cellsR01GM151373 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Qilong Ying · 2023 to 2026
$1.3M
Embryonic stem cell self-renewalR01GM129305 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YING, QILONG · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM129305NIGMS NIH HHS R01 GM151373U.S. Department of Health & Human Services | NIH | National Institute of Environmental Health Sciences (NIEHS) Z01ES102745
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41951855
PMCPMC13361078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.