Evidence map›Paper›PMID 41951809›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Mental disorders and osteoporosis treatment in patients with hip fracture-a Danish population-based cohort study.

Rikke Sommer Haaber, Bente Langdahl, Rob Nelissen, Simon Storgaard Jensen, Kjeld Andersen, Alma B Pedersen

Abstract read
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rikke Sommer HaaberDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. rsh@clin.au.dk.ORCID http://orcid.org/0009-0000-7614-3479
Bente LangdahlInstitute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Rob NelissenDepartment of Orthopedics, Leiden University Medical Center, Leiden, The Netherlands.
Simon Storgaard JensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Kjeld AndersenDepartment of Psychiatry, Odense University Hospital, Odense, Denmark.
Alma B PedersenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

Funding

Danmarks Frie Forskningsfond 4308-00074B
6 · The paper itself

Abstract

Using Danish registries, we identified 57,887 patients with hip fracture aged ≥ 65 without recent anti-osteoporosis medication (AOM) and examined whether mental disorders affect AOM initiation after hip fracture. One-year initiation ranged from 6.5 to 17.0% among patients with mental disorders compared to 21% in patients without mental disorder. Initiation remains suboptimal, highlighting required targeted interventions. PURPOSE: To evaluate the impact of mental disorders on the initiation of anti-osteoporosis medication (AOM) following hip fracture.

methodsUsing Danish medical registries, we identified patients aged ≥ 65, with no recent AOM use and a first-time hip fracture between 2010 and 2020 (n = 57,887). Mental disorders were categorized using a 10-year history of hospital contacts into no mental disorder, organic mental disorders, substance use, schizophrenic, mood, and anxiety disorders. The outcome was initiation of AOM defined by pharmacy dispensations and hospital treatment codes. Among patients without AOM use in the year prior to hip fracture, 1-year cumulative incidence functions (CIF) with 95% confidence intervals of initiation of AOM with death as a competing risk were calculated. Analyses were conducted overall and stratified by sex, age, previous fractures, somatic comorbidity, mental comorbidity, living arrangement, and calendar year.

resultsThe 1 year CIF of initiation of AOM after hip fracture was 20.8% (20.4-21.1) for patients with no mental disorder, 6.5% (6.0-7.1) for organic mental disorders, 17.0% (15.6-18.5) for substance use, 11.5% (9.5-13.8) for schizophrenic disorders, 14.8% (13.8-15.8) for mood, and 16.1% (14.4-17.9) for anxiety disorders. Higher initiation of AOM was seen in patients < 80 years, females, with previous fractures, in patients with less somatic comorbidity and no other mental comorbidities, cohabiting in their own home, and in more recent calendar years.

conclusionAOM initiation following hip fracture remains suboptimal. Patients with mental disorders were less likely to initiate AOM after hip fracture, highlighting a persistent gap in secondary fracture prevention among vulnerable populations.

Indexed as

Bone Density Conservation AgentsHip FracturesMental DisordersOsteoporosisOsteoporotic FracturesAgedAged, 80 and overComorbidityDenmarkFemaleHumansMaleProximal Femoral FracturesRegistriesUndertreatmentBone Density Conservation AgentsAnti-osteoporosis treatmentHip fractureInitiationMental disorderOsteoporosis

Identifiers

PMID41951809
PMCPMC13676504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.