Evidence map›Paper›PMID 41951781›Full record

ArticleInternational journal of obesity (2005)2026

Racial and ethnic disparities in type 2 diabetes: does visceral fat play a role? Evidence from the MESA study.

Tong Xia, Roch A Nianogo, QingZhao Yu, Tamara Horwich, Preethi Srikanthan, Kosuke Inoue, Matthew Allison, Zuo-Feng Zhang, Moyses Szklo, Karol E Watson and 1 more

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In one paragraph

Article in International journal of obesity (2005), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Tong XiaDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Roch A NianogoDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
QingZhao YuDepartment of Biostatistics, School of Public Health, Louisiana State University Health Sciences Center-New Orleans, New Orleans, LA, USA.
Tamara HorwichDepartment of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Preethi SrikanthanDepartment of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-9931-3407
Kosuke InoueDepartment of Social Epidemiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Matthew AllisonDepartment of Family Medicine and Public Health, School of Medicine, University of California San Diego, San Diego, CA, USA.
Zuo-Feng ZhangDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Moyses SzkloDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Karol E WatsonDepartment of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Liwei ChenDepartment of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA. cliwei86@ucla.edu.ORCID http://orcid.org/0000-0002-8458-5661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn the United States, racial and ethnic minorities have higher risk of developing type 2 diabetes (T2D) than Whites. One hypothesis is that some minorities (e.g., Hispanics, Asians) have more visceral fat than Whites in a sex-specific manner. We aimed to test this hypothesis by examining to what degree racial differences in T2D were explained by visceral fat in males and females.

methodsThis prospective cohort included 1457 participants (51.2% females) from the Multi-Ethnic Study of Atherosclerosis (MESA) cohort who had visceral fat measured by computed tomography and followed for incident T2D from 2002-2005 to 2020. We assessed associations of race and T2D risk using Cox proportional hazards regressions and estimated associations explained by visceral fat using natural mediation effects, stratified by sex.

resultsControlling for confounders, compared with White participants, T2D risk was higher in Hispanic females (HR 1.77, 95% CI 1.17-2.69), Chinese females (1.91, 1.15-3.15), Black females (1.59, 1.02-2.49), and Hispanic males (1.82, 1.20-2.76). Estimates for Black males (1.48, 0.92-2.38) and Chinese males (0.86, 0.48-1.55) were not statistically significant. By sex, Hispanic females [mean difference (SE): 22.72 (5.68)] had higher visceral fat (cm

conclusionVisceral fat explained one-fifth of racial and ethnic differences in T2D comparing Hispanic females to White females and may contribute to Hispanic females' higher T2D risk.

Indexed as

Diabetes Mellitus, Type 2EthnicityHealth Status DisparitiesIntra-Abdominal FatAgedAsianBlack or African AmericanFemaleHispanic or LatinoHumansMaleMiddle AgedProspective StudiesRisk FactorsSex FactorsUnited States

Identifiers

PMID41951781
PMCPMC13286983

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