Evidence map›Paper›PMID 41951575›Full record

ArticleMicrosystems & nanoengineering2026

A cylindrical projection lithography-fabricated flexible on-catheter in situ integrated sensor for continuous in-artery blood pressure monitoring.

Fengming Ye, Jianwei Hou, Xuanyu Li, Jie Ni, Mengqiu Li, Jiaxiang Wang, Yangtao Yu, Zhiyuan Hu, Yahui Li, Faheng Zang and 6 more

Abstract read
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In one paragraph

Article in Microsystems & nanoengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Fengming YeNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.ORCID http://orcid.org/0000-0002-6290-6612
Jianwei HouNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Xuanyu LiSchool of Ocean and Civil Engineering, Shanghai Jiao Tong University, Shanghai, PR China.
Jie NiNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Mengqiu LiNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Jiaxiang WangNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Yangtao YuNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Zhiyuan HuNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Yahui LiSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore.
Faheng ZangNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.ORCID http://orcid.org/0000-0002-1173-6553
Guifu DingNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China.
Bin SunInstitute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences (CAS), Shenzhen, PR China.
Kaiming SuDepartment of Otolaryngology-Head and Neck Surgery, Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
Xiaojun GuoSchool of Integrated Circuits (School of Information Science and Electronic Engineering), Shanghai Jiao Tong University, Shanghai, PR China.
Fuyou LiangSchool of Ocean and Civil Engineering, Shanghai Jiao Tong University, Shanghai, PR China.
Zhuoqing YangNational Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University, Shanghai, PR China. yzhuoqing@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-9635-6145

Funding

Shanghai Science and Technology Development Foundation (Shanghai Science and Technology Development Fund) 25JD1402600SJTU | School of Medicine, Shanghai Jiao Tong University (School of Medicine, Shanghai Jiao Tong University) YG2024LC07
6 · The paper itself

Abstract

Continuous and accurate blood pressure monitoring is vital for the diagnosis and management of life-threatening cardiovascular diseases. Conventional fluid-filled catheter systems are fundamentally constrained by distortion, infection risks, and limited portability. In parallel, Micro-Electro-Mechanical System (MEMS) sensors assembled to catheters face miniaturization bottlenecks and packaging complexity. Here, we present a flexible on-catheter interventional pressure sensor (CIPS), leveraging suspended-graphene arrays for pressure sensing and dual polymer encapsulation layers for hermetic and waterproof encapsulation. The highly integrated CIPS with compact architecture is enabled by cylindrical projection lithography (CPL)-based 3D in situ MEMS fabrication process. By introducing interdigital electrodes (IDEs) in sensitive areas and optimizing structural parameters, CIPS delivers an ultrafast response (<0.36 s), exceptional sensitivity (3.5 × 10⁻⁶·mmHg⁻¹), and a broad detection range (6-380 mmHg), outperforming state-of-the-art suspended-graphene pressure sensors. The dual-layer polymer encapsulation strategy ensures the hermetic and waterproof integrity of CIPS. Crucially, CIPS enables real-time monitoring of arterial pressure in the rat abdominal aorta, marking the first demonstration of suspended graphene in animal-level bioelectronic sensing. This work has also underscored the translational potential for CPL-based 3D in situ MEMS fabrication strategy.

Identifiers

PMID41951575
PMCPMC13061948

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