Global Inventory of Fluoropolymer Production Plants and Their Associated PFAS Environmental Contamination.

Fluoropolymers are widely used across sectors, but their production is associated with emissions of perfluoroalkyl and polyfluoroalkyl substances (PFASs), which are mobile, persistent, and toxic. In this work, we compiled a global inventory of fluoropolymer production plants (FPPs) and assembled PFAS concentration measurements for various media in their vicinity. We identified 52 currently operating FPPs across 11 countries and 41 cities. For 12 FPPs, in 12 different cities, there are peer-reviewed site-specific PFAS measurements specifically attributed to the FPP. At these 12 sites, at least 236 individual PFASs have been detected across multiple environmental media, including surface water, groundwater, air, dust, soils, sediments, plants, animals, and humans, with reported detections at distances of up to approximately 150 km from FPPs. Perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl ether carboxylic acids (PFECAs) were most frequently measured, often at concentrations two to three orders of magnitude higher than those measured in regions without nearby FPPs. Using high-resolution population data, we estimate that approximately 14 ± 2 million people (uncertainty reflecting ± 10 km uncertainty in facility locations) live within 10 km of an FPP. These people are potentially affected by FPP-associated contamination, with the largest population shares in China (≈52%), Japan (≈24%), Europe (≈13%), and the United States (≈9%). These regional proportions largely mirror differences in population density and the number of identified production facilities. This inventory reveals the large and complex global scale of PFAS contamination from fluoropolymer production, underscoring the need for expanded systematic monitoring and risk management efforts, including regulation.