Evidence map›Paper›PMID 41950437›Full record

ArticleJCO clinical cancer informatics2026

Childhood Cancer Data Initiative Participant Index: Mapping Pediatric Cancer Data to Facilitate Cross-Study Integrated Analysis.

Subhashini Jagu, Jaime M Guidry Auvil, Mark D Cunningham, Ricardo Flores Jimenez, Martin L Ferguson, Malcolm A Smith, Douglas S Hawkins, Todd A Alonzo, Thalia Beeles, Brigitte C Widemann and 2 more

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Subhashini JaguOffice of Data Sharing, National Cancer Institute, Bethesda, MD.ORCID 0000-0002-3888-2390
Jaime M Guidry AuvilOffice of Data Sharing, National Cancer Institute, Bethesda, MD.
Mark D CunninghamFrederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD.
Ricardo Flores JimenezEssential Software Inc, Gaithersburg, MD.
Martin L FergusonFrederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc, Frederick, MD.ORCID 0000-0002-2050-4199
Malcolm A SmithClinical Investigations Branch, National Cancer Institute, Bethesda, MD.ORCID 0000-0001-9880-9876
Douglas S HawkinsChildren's Oncology Group, Monrovia, CA.ORCID 0000-0003-3602-1375
Todd A AlonzoDepartment of Preventative Medicine, University of Southern California, Los Angeles, CA.
Thalia BeelesChildren's Oncology Group, Monrovia, CA.ORCID 0009-0004-6189-296X
Brigitte C WidemannPediatric Oncology Branch/Center for Cancer Research, National Cancer Institute, Bethesda, MD.ORCID 0000-0002-9198-7175
Warren A KibbeData Science and Strategy, National Cancer Institute, Bethesda, MD.ORCID 0000-0001-5622-7659
Gregory H ReamanDivision of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD.ORCID 0000-0002-6698-4503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo facilitate integrated multimodal data analysis, it is critical to connect data from multiple sources to address multifaceted research questions, better understand disease biology and natural history, develop new therapies, and improve existing treatments. The Childhood Cancer Data Initiative (CCDI) Participant Index, an application programming interface, aims to address this challenge by providing a digital ID mapping and matching service which collects and cross-references all known IDs associated with a participant.

methodsA variety of retrospective and prospective data collected through the CCDI Data Ecosystem equal or surpass the complexity of patient data systems in large health care organizations. The CCDI Data Ecosystem includes participant data collected under multiple protocols and at multiple sites, which often results in the same participant being associated with multiple IDs depending on the source, time, or other variables. CCDI is exploring ways to integrate diverse data types (such as genomic, proteomic, imaging, transcriptomic, clinical trial, and electronic health record data), collected over time and from different sources at the participant level, while ensuring privacy protection.

resultsThis mapping allows researchers to access a more complete picture of a participant, even when data are collected at different time points, organizations, protocols, and consents.

conclusionThis facilitates the creation of a connected data ecosystem and promotes data reuse, which, in turn, can accelerate research and improve participant outcomes.

Indexed as

NeoplasmsChildDatabases, FactualElectronic Health RecordsHumans

Identifiers

PMID41950437
PMCPMC13068442

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.