Evidence map›Paper›PMID 41950013›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Expert consensus on communicating tau PET results to persons living with MCI or dementia: Findings from a modified Delphi study.

Claire Erickson, Kyra S O'Brien, Emily A Largent, Kristin Harkins, Cameron Coykendall, Melanie Kleid, Justin T Clapp, Jason Karlawish

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Claire EricksonBanner Alzheimer's Institute, Phoenix, Arizona, USA.
Kyra S O'BrienDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Emily A LargentDepartment of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Kristin HarkinsDivision of Geriatrics, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Cameron CoykendallDivision of Geriatrics, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Melanie KleidDivision of Geriatrics, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Justin T ClappDepartment of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Jason KarlawishDepartment of Medical Ethics and Health Policy, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Funding

National Institute On Aging of the National Institutes of Health P30AG072980
6 · The paper itself

Abstract

introductionThere is interest in incorporating tau imaging into clinical care because it provides unique diagnostic and prognostic information. Yet, clinicians lack guidance on communicating results.

methodsWe conducted a modified Delphi process with practicing US-based expert clinicians in human tau imaging. Expert clinicians were interviewed to elicit input on best practices for communicating tau positron emission tomography (PET) results to cognitively impaired patients. These data were used to develop candidate practices and statements, which expert clinicians rated across two online survey rounds.

resultsEighteen expert clinicians completed interviews and both surveys. They reached consensus on 12 practices - like showing individuals their tau PET scan images - and eight statements for communicating tau PET results - one for tau alone, three for concordant amyloid and tau results, and four for discordant amyloid and tau results - to cognitively impaired patients. DISCUSSION: This study provides novel consensus recommendations for communicating tau PET results to cognitively impaired patients.

Indexed as

Cognitive DysfunctionConsensusDementiaPositron-Emission Tomographytau ProteinsDelphi TechniqueFemaleHumansMaletau Proteinsexpert consensuspatient communicationtau positron emission tomography

Identifiers

PMID41950013
PMCPMC13060757

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