Evidence map›Paper›PMID 41950011›Full record

ArticleSTAR protocols2026

Protocol for inducing focal striatal stroke in mice using photothrombosis.

Bridget R Boyle, Eileen Collyer, Andrea P Berghella, Elena Blanco-Suarez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bridget R BoyleDepartment of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Eileen CollyerDepartment of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Andrea P BerghellaDepartment of Neuroscience, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Elena Blanco-SuarezDepartment of Biology, San Diego State University, San Diego, CA 92182, USA. Electronic address: eblancosuarez@sdsu.edu.

Funding

American Heart Association-American Stroke Association 23IPA1055207American Heart Association-American Stroke Association 937695
6 · The paper itself

Abstract

Here, we present a protocol for inducing focal striatal stroke in mice using photothrombosis. We describe steps for photothrombotic striatal surgery, magnetic resonance imaging, open field behavioral assessment of stroke-induced motor deficits, and post-stroke monitoring. We then detail procedures for tissue collection and immunofluorescence. This protocol provides a standardized approach for consistently modeling striatal stroke in mice, enabling mechanistic studies and preclinical therapeutic testing.

Indexed as

Corpus StriatumStrokeAnimalsDisease Models, AnimalMagnetic Resonance ImagingMiceBehaviorMolecular BiologyNeuroscience

Identifiers

PMID41950011
PMCPMC13091047

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.