Evidence map›Paper›PMID 41949771›Full record

ArticlePlant cell reports2026

Salicylic acid-mediated biosynthesis of anti-oomycete diterpenoids in Euphorbia lathyris L. suspension cells.

Pirui Li, Xi Sun, Guodong Zhang, Bi Wang, Chenxing Xiao, Mei Tian, Shu Xu, Hui Liu, Xu Feng, Linwei Li and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Plant cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pirui Li *Jiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Xi Sun *Jiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Guodong ZhangJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Bi WangJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Chenxing XiaoJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Mei TianJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Shu XuJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Hui LiuHenan Jinling Honeysuckle Pharmaceutical Co., Ltd., Xinxiang Henan, 453300, China.
Xu FengJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Linwei LiJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China. xt_llw@163.com.
Wanli ZhaoJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China. zhaowanlitcm@126.com.
Yu ChenJiangsu Key Laboratory for Conservation and Utilization of Plant Resources, Jiangsu Province Engineering Research Center of Eco-Cultivation and High-Value Utilization of Chinese Medicinal Materials, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China. ychen@jib.ac.cn.

Funding

National Natural Science Foundation of China 32200326National Natural Science Foundation of China 32270404National Natural Science Foundation of China 32300337Open Fund of the Jiangsu Key Laboratory for Plant Resources Research and Utilization JSPKLB202309Scientific Fund of Nanjing Botanical Garden Mem. Sun Yat-Sen JSPKLB202501Talent Fund of the Jiangsu Institute of Botany JIBTF202304the Jiangsu Provincial Key Research and Development Program BE2022370
6 · The paper itself

Abstract

key messageSalicylic acid treatment significantly enhances the production of bioactive Euphorbia diterpenoids in Euphorbia lathyris suspension cultures by activating defense and diterpenoid biosynthetic pathways, including upregulating the key acyltransferase gene ElBAHD1. The medicinal plant Euphorbia lathyris produces pharmacologically active diterpenoids, but the content of which is limited in Euphorbia plants. An efficient suspension culture system of E. lathyris was established to enhance the production of bioactive diterpenoids. Salicylic acid (SA) treatment (550 μM, 10 days) significantly enhanced the production of lathyrane-type diterpenoids jolkinol A' (1), jolkinol A (2), jolkinol B (5), and a new 16-hydroxylated jolkinol A derivative (7). In particular, the volumetric yield of jolkinol A (2) was achieved to 47.00 mg L

Indexed as

DiterpenesEuphorbiaSalicylic AcidCells, CulturedGene Expression Regulation, PlantPlant ProteinsDiterpenesPlant ProteinsSalicylic AcidDiterpenoidsEuphorbia lathyrisJolkinol ASalicylic acidSuspension cell

Identifiers

PMID41949771

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.