Evidence map›Paper›PMID 41949749›Full record

Trial reportIndian pediatrics2026

Respiratory Stabilization for Successful Intubation in Neonates: A Randomized Controlled Trial.

Deeksha Gupta, Poonam Singh, Mayank Priyadarshi, Suman Chaurasia, Sriparna Basu

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Indian pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Deeksha GuptaDepartment of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.
Poonam SinghDepartment of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India. drpoonamujn@gmail.com.
Mayank PriyadarshiDepartment of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.
Suman ChaurasiaDepartment of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.
Sriparna BasuDepartment of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 249203, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMaintenance of non-invasive respiratory support during endotracheal intubation (ETI) is a feasible intervention to prevent procedure-related physiological instability (PI) in neonates. However, the evidence for its use is conflicting. The present study evaluated the effects of continuing pre-existing respiratory support during ETI in neonates compared to standard care.

methodsNeonates (≥ 26 weeks) requiring ETI in the neonatal intensive care unit (NICU) were randomized to undergo ETI either on respiratory support (intervention; n = 75) or in room air (control; n = 75) using a computer-generated variable block random sequence, stratified according to gestational age (< 32 weeks and ≥ 32 weeks). Neonates with bradycardia (heart rate, HR < 100/minute), life-threatening congenital anomalies and those requiring intubation on emergency basis, were excluded. The primary outcome was first attempt successful intubation without PI (defined as desaturation, absolute fall in peripheral oxygen saturation (SpO

resultsThe baseline maternal and neonatal variables were comparable between both groups. The primary outcome was achieved in 73.3% and 62.7% of the neonates in the intervention and control group, respectively [relative risk (95% confidence interval) 1.3 (0.7-1.7); P = 0.161]. Minimum SpO

conclusionContinuation of pre-existing non-invasive respiratory support during ETI in neonates better maintained SpO

Indexed as

Intubation, IntratrachealBradycardiaFemaleHeart RateHumansInfant, NewbornIntensive Care Units, NeonatalMaleOxygen SaturationBradycardiaEndotracheal intubationNeonatesPhysiological instabilityRespiratory support

Identifiers

PMID41949749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.