ArticleInternational ophthalmology2026
Tenon Patch Graft in Management of Impending or Full Thickness Corneal Perforation in Pediatric Patients.
Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the outcomes of autologous Tenon's patch graft (TPG) in impending or full thickness corneal perforations in pediatric patients with infectious keratitis. PATIENTS AND
methodsIn this prospective, interventional case series, 26 eyes of 26 children (age ≤ 16 years) presenting with 3-5 mm impending or full thickness corneal perforations secondary to bacterial or fungal keratitis underwent autologous TPG. Tenon's tissue was harvested, fashioned to slightly exceed the defect diameter, and secured with interrupted 10-0 nylon sutures, followed by bandage contact lens placement. Postoperative topical antimicrobial therapy was tailored to the causative organism. Patients were examined preoperatively and followed up for 3 months. Outcome measures included best corrected visual acuity (BCVA), Seidel testing, anterior chamber depth evaluation, time of epithelialization and scar formation, and assessment by anterior segment optical coherence tomography (AS-OCT).
resultsThe cohort comprised 14 males and 12 females, mean age 9.4 ± 3.3 years. At three months, 24 eyes (92.3%) achieved complete anatomical healing, with 25 eyes (96.2%) maintaining a formed anterior chamber and testing Seidel negative. Mean LogMAR BCVA improved from 1.75 ± 0.59 to 1.32 ± 0.56 at 3 months (p = 0.001). AS-OCT demonstrated complete stromal integration without leucoma in 17 eyes (65.4%) and healed grafts with adherent leucoma in 7 eyes (26.9%). Two eyes (7.7%) required therapeutic penetrating keratoplasty for ongoing infection; one eye (3.8%) needed suture augmentation. No major intraoperative complications occurred.
conclusionAutologous Tenon's patch graft for medium sized infectious corneal perforations in pediatric patients yields high anatomical success, significant visual improvement, and minimal complications. It represents a valuable option in settings where donor tissue is scarce or emergency intervention is required.
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