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SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Outcomes and complications of bipolar fusionless constructs for early-onset scoliosis: a systematic review.

Sergio De Salvatore, Paolo Brigato, Davide Palombi, Gian Mario Sangiovanni, Leonardo Oggiano, Umile Giuseppe Longo, Laura Ruzzini, Fabrizio Donati, Pier Francesco Costici

Abstract readSystematic Review
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In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sergio De SalvatoreDepartment of Orthopaedic and Traumatology, Bambino Gesù Children's Hospital, Rome, Italy. sergio.desalvatore@gmail.com.
Paolo BrigatoCampus Bio-Medico University, Rome, Italy.
Davide PalombiAgostino Gemelli University, Rome, Italy.
Gian Mario SangiovanniSapienza University of Rome, Rome, Italy.
Leonardo OggianoDepartment of Orthopaedic and Traumatology, Bambino Gesù Children's Hospital, Rome, Italy.
Umile Giuseppe LongoCampus Bio-Medico University, Rome, Italy.
Laura RuzziniDepartment of Orthopaedic and Traumatology, Bambino Gesù Children's Hospital, Rome, Italy.
Fabrizio DonatiDepartment of Orthopaedic and Traumatology, Bambino Gesù Children's Hospital, Rome, Italy.
Pier Francesco CosticiDepartment of Orthopaedic and Traumatology, Bambino Gesù Children's Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly-onset scoliosis (EOS) is a spinal deformity manifesting before age ten, often linked to neuromuscular conditions. Traditional Growing Rod (TGR) techniques, while effective, are associated with high complication rates and require frequent surgeries. Bipolar fixation techniques, which utilize ilio-sacral screws and sliding rods, have emerged as a less invasive alternative, aiming to preserve spinal growth. This systematic review evaluates the safety and efficacy of bipolar fixation in predominantly neuromuscular EOS and mixed pediatric cohorts reported in the current literature, exploring potential benefits and complications.

methodsFollowing PRISMA guidelines, a comprehensive search of electronic databases up to April 2025 identified relevant studies. Terms included EOS, neuromuscular scoliosis, and bipolar fixation techniques. The MINORS score assessed the risk of bias in the studies. A meta-analysis was intentionally not performed due to probable overlap of patient cohorts across studies from the same surgical team; therefore, a structured narrative synthesis was undertaken.

resultsNine studies with 629 patients were included, with a mean age at surgery of 10.7 years. The primary outcome, the percentage of Cobb angle correction, showed a mean preoperative angle of 75.1°, with postoperative angles ranging from 21.0° to 43.0° (average value of 33.3°). Complication rates, mainly mechanical failures and infections, averaged 36%. Mechanical failure rates varied, but infection rates were consistent across studies.

conclusionBipolar fixation techniques appear to offer a potential alternative for the treatment of early-onset scoliosis, particularly in neuromuscular cases. However, the current evidence is limited by low methodological quality and a strong predominance of studies from a single surgical team, often involving overlapping patient cohorts. Although the technique demonstrates satisfactory radiographic correction, the complication rate remains high, and the findings cannot yet be generalized. Robust, multicenter comparative studies are needed before definitive conclusions can be drawn regarding the safety and efficacy of this approach.

Indexed as

Orthopedic ProceduresPostoperative ComplicationsScoliosisAge of OnsetBone ScrewsChildHumansSpinal FusionTreatment OutcomeBipolar FixationEarly Onset ScoliosisGrowing Rod

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.