Evidence map›Paper›PMID 41949505›Full record

ArticleJACC. Case reports2026

Safety and Feasibility of Left Bundle Branch Area Pacing Following Transcatheter Tricuspid Valve Replacement.

Mohammed Kamareddine, Farah Olleik, Colleen Hanley, Scott Goldman, William A Gray, Ali Keramati

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed KamareddineLankenau Medical Center, Wynnewood, Pennsylvania, USA.
Farah OlleikLankenau Medical Center, Wynnewood, Pennsylvania, USA.
Colleen HanleyLankenau Medical Center, Wynnewood, Pennsylvania, USA.
Scott GoldmanLankenau Medical Center, Wynnewood, Pennsylvania, USA.
William A GrayLankenau Medical Center, Wynnewood, Pennsylvania, USA.
Ali KeramatiLankenau Medical Center, Wynnewood, Pennsylvania, USA. Electronic address: KeramatiA@mlhs.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter tricuspid valve replacement (TTVR) is a novel therapy for severe tricuspid regurgitation. However, conduction disturbances requiring pacemaker implantation occur in up to 24.7% of patients. Left bundle branch area pacing (LBBAP) has not been systematically evaluated post-TTVR, where lead passage across the prosthesis may compromise valve integrity. The objective of this paper was to report the feasibility, safety, and performance of LBBAP after TTVR. CASE SUMMARY: Two pacemaker-naïve patients requiring pacing post-TTVR were retrospectively analyzed. DISCUSSION: Both patients underwent TTVR and developed high-grade atrioventricular block within 72 hours. LBBAP was successful in both cases with no procedural-related complications. At 30 days, pacing parameters remained unchanged with no device-related adverse events. Echocardiography at 1 and 30 days demonstrated ≤ mild tricuspid regurgitation, no lead-valve interaction, and stable right ventricular function. TAKE-HOME MESSAGES: LBBAP post-TTVR is feasible with excellent short-term safety and performance while maintaining valve integrity. Our series reinforces its safety and adds systematic echocardiographic follow-up.

Indexed as

atrioventricular blockconduction system pacinglead-valve interactionleft bundle branch area pacing (LBBAP)transcatheter tricuspid valve replacement (TTVR)

Identifiers

PMID41949505
PMCPMC13350652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.