Evidence map›Paper›PMID 41949311›Full record

ArticleJournal of the American Chemical Society2026

Radical Sampling Enabled Saturated N-Heterocycle Cyclization.

Qinyan Cai, Noah B Bissonnette, Saegun Kim, Thomas Knauber, Gary M Chinigo, David C Blakemore, David W C MacMillan

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qinyan CaiMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0002-5908-2560
Noah B BissonnetteMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.
Saegun KimMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.
Thomas KnauberPfizer Research and Development, Groton, Connecticut 06340, United States.ORCID 0000-0002-3354-3322
Gary M ChinigoPfizer Research and Development, Groton, Connecticut 06340, United States.ORCID 0009-0009-6130-6808
David C BlakemorePfizer Research and Development, Groton, Connecticut 06340, United States.
David W C MacMillanMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.ORCID 0000-0001-6447-0587

Funding

Photoredox Catalysis Applications in Organometallics and Chemical BiologyR35GM134897 · NIGMS · PRINCETON UNIVERSITY · PI David W MacMillan · 2020 to 2026
$6.3M
NIGMS NIH HHS R35 GM134897
6 · The paper itself

Abstract

Nitrogen-containing saturated heterocycles are essential structural motifs in many small molecule drugs, and the development of methods to rapidly access these scaffolds remains highly desirable. A modular and streamlined strategy for accessing these motifs involves

Identifiers

PMID41949311
PMCPMC13107455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.