Evidence map›Paper›PMID 41948899›Full record

SynthesisHead & neck2026

Oncological Safety of the Submental Artery Island Flap for Oral Reconstruction: A Systematic Review and Meta-Analysis.

Shafaq Taseen, Muhammad Fazal Hussain Qureshi, Munib Abbas, Shayan K Ghaloo, Muhammad Wasif, Haissan Iftikhar, Hamdan A Pasha, Rahim Dhanani

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Head & neck, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shafaq TaseenDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0001-6253-3679
Muhammad Fazal Hussain QureshiCentre for Patient Safety, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0002-4416-4379
Munib AbbasClinical Trials Unit, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0002-1057-7036
Shayan K GhalooDepartment of ENT, Head & Neck Surgery, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.ORCID https://orcid.org/0000-0002-3237-0669
Muhammad WasifDepartment of ENT, Head & Neck Surgery, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.ORCID https://orcid.org/0000-0002-3760-484X
Haissan IftikharDepartment of ENT, Head & Neck Surgery, University Hospital Northamptonshire NHS Group, Northampton, UK.ORCID https://orcid.org/0000-0003-3266-4015
Hamdan A PashaENT & Head and Neck Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0001-6349-7024
Rahim DhananiENT & Head and Neck Surgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0002-5519-862X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubmental artery island flap is a pedicled regional flap which is used as one of the quicker reconstructive options for oral cavity defects. However, concerns about its oncological safety have been raised due to the proximity of the submental lymph nodes, which may harbor metastatic deposits. This study aimed to systematically evaluate the oncological safety of the SAIF oral cavity reconstruction.

methodsA systematic review and meta-analysis was conducted according to the PICO model. Studies were included if they assessed the oncological safety of the SAIF in oral cavity reconstruction.

resultsThe use of SAIF for oral cavity reconstruction appears to provide reasonable oncological safety in terms of locoregional recurrence. The overall pooled recurrence rate across the studies was 16% (95% CI: 14%-18%).

conclusionThis systematic review demonstrates that the submental artery island flap is an oncologically safe and reliable reconstructive option for oral cavity defects following OSCC resection in carefully selected patients.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsPlastic Surgery ProceduresSurgical FlapsHumansNeoplasm Recurrence, Localoncological safetyoral canceroral cavityreconstructionsubmental flap

Identifiers

PMID41948899
PMCPMC13432013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.