Evidence map›Paper›PMID 41948778›Full record

ArticleJPRAS open2026

Association between procalcitonin and mortality in patients with necrotizing fasciitis: A single-center retrospective study.

Alperen S Bingoel, Khaled Dastagir, Nele Schmitt, Najib Dastagir, Mustafa Salim, Peter M Vogt, Doha Obed

Abstract read
In one paragraph

Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alperen S BingoelDivision of Plastic Surgery, Department of Trauma, Orthopedic and Plastic Surgery, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
Khaled DastagirDepartment of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Nele SchmittDepartment of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Najib DastagirDepartment of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Mustafa SalimDepartment of Human Genetics, Hannover Medical School, Hannover, Germany.
Peter M VogtDepartment of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
Doha ObedDepartment of Plastic, Aesthetic, Hand and Reconstructive Surgery, Burn Center, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Necrotizing fasciitis (NF) is a rapidly progressing, life-threatening soft tissue infection. Procalcitonin (PCT) has emerged as a promising biomarker for early diagnosis and prognosis in severe infections. Methods: We performed a retrospective analysis of 62 patients with confirmed NF treated at a high-volume Department of Plastic Surgery between January 2005 and May 2024. Clinical parameters, laboratory values, and surgical outcomes were evaluated. Patients were stratified into survivors and non-survivors. Results: Elevated PCT levels at admission were significantly associated with in-hospital mortality ( Conclusion: Serum PCT levels at admission may serve as a valuable prognostic marker in NF. Once infection control is achieved, reconstructive surgical interventions appear to be safe and do not influence survival.

Indexed as

BiomarkerMortalityNecrotizing fasciitisProcalcitoninReconstructive surgery

Identifiers

PMID41948778
PMCPMC13051722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.