ArticleOTO open
Predicting Behavior of Cutaneous Head and Neck Squamous Cell Carcinoma in Transplant Recipients.
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Head/neck location and immunosuppression are independent risk factors related to cutaneous head and neck squamous cell carcinomas (cHNSCCs) in solid organ transplant recipients (SOTRs). Traditional staging criteria underperform in risk stratification. We aim to identify the utility of clinicopathologic factors for risk stratification of cHNSCCs in SOTRs. Study Design: Retrospective cohort study. Setting: Single tertiary center. Methods: SOTRs with surgically resected cHNSCCs between 2009 and 2019 were reviewed. Deeply invasive cHNSCCs extended deep to the subcutis. Data were extracted from electronic records. Overall survival was analyzed by level of invasion and transplant type using Mantel-Cox test and by age at transplant and age at first posttransplant cHNSCC using univariate Cox regression. Level of invasion was evaluated using unpaired Results: Of 77 identified patients, 44 (100% White, 97.7% non-Hispanic, 81.8% male) met criteria. Sixteen developed deep invasion. Deep invasion correlated with decreased overall survival ( Conclusion: Deeply invasive cHNSCCs are associated with decreased overall survival in SOTRs. Age at transplant approaches significance for deep invasion. Data on immunosuppression and genetic analysis may further enhance prognostication.
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