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Prognostic Determinants in De Novo Sinonasal Squamous Cell Carcinoma: A Retrospective Study.
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Patients diagnosed with de novo sinonasal squamous cell carcinoma (DN-SSCC) generally present at an advanced stage and have a poor prognosis. The study aimed to summarize and analyze the outcomes of DN-SSCC patients. Study Design: Retrospective cross-sectional study. Setting: Single-center clinical database. Methods: Overall survival was assessed with Kaplan-Meier analyses and Cox proportional hazard regression analyses for patients diagnosed with DN-SSCC between 2010 and 2018. Results: Long-term follow-up was completed for 85 out of 112 patients. The distribution of cancer stages was as follows: 1.8% in stage Ⅰ, 7.1% in stage Ⅱ, 23.2% in stage Ⅲ, and 67.9% in stage Ⅳ. Ocular invasion was present in 50.9% and intracranial invasion in 23.2%. Significant intergroup differences in T-stage ( Conclusions: Patients receiving Surgery + CT/RT had better prognoses. This therapeutic modality is recommended for advanced-stage patients, especially those with positive resection margins.
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