Evidence map›Paper›PMID 41948585›Full record

ArticleFrontiers in medicine2026

Neuromotor frailty phenotype and fall risk in geriatrics with knee osteoarthritis: a cross-sectional analysis of physical therapy performance and psychometric outcomes.

Batool Abdulelah Alkhamis, Basant Hamdy Elrefaey, Ravi Shankar Reddy, Wafaa Mahmoud Amin, Esraa M Fayed, Joud Fahad Albishri, Taif Ibrahim Asiri, Abdulaziz Ali Matiq, Hany Mahmoud Fares

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Batool Abdulelah AlkhamisProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Basant Hamdy ElrefaeyProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Ravi Shankar ReddyProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Wafaa Mahmoud AminDepartment of Physical Therapy, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Esraa M FayedDepartment of Physical Therapy, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Joud Fahad AlbishriProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Taif Ibrahim AsiriProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Abdulaziz Ali MatiqProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Hany Mahmoud FaresDepartment of Physical Therapy, Abha International Private Hospital, Abha, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Falls are a leading cause of morbidity in older adults with knee osteoarthritis (KOA), yet current assessment strategies often lack the specificity needed to identify those at the most significant risk. The integration of physical therapy (PT) outcome measures may enhance fall risk stratification by capturing functional impairments across multiple domains. To compare neuromotor frailty profiles between older adult fallers and non-fallers with KOA using standardized PT assessments, and to evaluate the predictive validity and latent structure of these measures for fall risk classification. Methods: In this cross-sectional study, 128 community-dwelling older adults with KOA (64 fallers, 64 non-fallers) completed a battery of PT outcome measures, including the Timed Up and Go Dual Task (TUG-DT), Four Square Step Test (FSST), Falls Efficacy Scale-International (FES-I), Functional Gait Assessment (FGA), Short Physical Performance Battery (SPPB), and others. Group differences were assessed using independent Results: Fallers showed significantly poorer performance across all PT measures, including slower TUG-DT (17.90 ± 3.42 vs. 13.42 ± 3.10 s, Conclusion: A multidimensional battery of PT outcome measures effectively differentiates fallers from non-fallers and characterizes the neuromotor frailty phenotype in older adults with KOA. These measures demonstrate strong discriminative performance for fall status and provide clinically relevant indicators of fall risk as a multidimensional construct.

Indexed as

fallsgeriatric assessmentknee osteoarthritismobility limitationphysical therapy modalitiespostural balance

Identifiers

PMID41948585
PMCPMC13050852

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.