SynthesisFrontiers in medicine2026
Global trends and hotspots of natural medicines for pathological scar treatment: a visualized bibliometric analysis (2008-2025).
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The therapeutic role of natural medicines in pathological scars has received widespread attention in recent years. However, there is no systematic bibliometric study to analyze the research hotspots and trends in this field. Purpose: This study aimed to provide researchers with a comprehensive summary of natural medicines in pathological scars; visualize the current research status, hotspot directions, and development trends; and offer references for subsequent research and clinical translation in this field. Methods: Publications related to the topic from 2008 to 2025 were retrieved from the WOSCC and PubMed databases. Bibliometric analyses were performed using VOSviewer, CiteSpace, Scimago Graphica, Microsoft Office Excel, and GraphPad Prism. Results: Global publications on natural medicines for pathological scar treatment have steadily increased. A total of 234 papers were retrieved, contributed by 1,395 authors from 396 institutions across 39 countries/regions. China far outnumbered other countries in publication output, with four of the top five authors residing in China. Shanghai Jiao Tong University ranked first among institutions by publication count. The most recent keywords-drug delivery, transdermal delivery, antioxidant, angiogenesis, and the transforming growth factor-β (TGF-β)/Smad-suggest emerging research frontiers. Conclusion: Research on natural medicines in pathological scars is still in a developmental stage. This is the first bibliometric analysis in this domain, highlighting the current hotspots and shedding light on future research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.