Evidence map›Paper›PMID 41948541›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

The influence of bilingualism on the assessment and treatment of an Italian-English speaker with the logopenic variant of PPA.

Roberta Tomasoni, Gaia C Santi, Serena Tagliente, Chiara Griseta, Simona Aresta, Allegra Benzini, Paola Santacesaria, Cinzia Palmirotta, Maria Luisa Mandelli, Stephanie Grasso and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The include network: Advancing cross-linguistic equity in brain health research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Roberta TomasoniIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Gaia C SantiIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Serena TaglienteIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Chiara GrisetaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Simona ArestaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Allegra BenziniIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Paola SantacesariaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Cinzia PalmirottaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.
Maria Luisa MandelliMemory and Aging Center University of California San Francisco San Francisco California USA.
Stephanie GrassoDepartment of Speech, Language and Hearing Sciences University of Texas at Austin Austin Texas USA.
Petronilla BattistaIstituti Clinici Scientifici Maugeri IRCCS, Laboratory of Neuropsychology, Bari Institute Bari Italy.ORCID https://orcid.org/0000-0002-3120-1214

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Primary Progressive Aphasia: Cognition, Anatomy and ProgressionRF1NS050915 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORNO TEMPINI, MARIA LUISA · 2022 to 2022
$4.7M
The impact of bilingualism on cognitive reserve/resilience using socio-demographically and linguistically diverse populationsR01AG080469 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Suvarna Alladi, Ganesh M Babulal · 2023 to 2026
$4.0M
Word fluency task performance as a marker of Alzheimer’s disease in Tagalog/English bilingual speakerR01AG080396 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jessica Anne Deleon · 2023 to 2026
$3.3M
Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive AphasiaR01AG080470 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI Stephanie M Grasso · 2023 to 2026
$2.8M
NIA NIH HHS P01 AG019724NIA NIH HHS R01 AG080396NIA NIH HHS R01 AG080469NIA NIH HHS R01 AG080470NINDS NIH HHS RF1 NS050915
6 · The paper itself

Abstract

introductionThe impact of bilingualism on speech-language assessment and therapy in primary progressive aphasia (PPA) remains underexplored, despite its suggested influence on disease presentation.

methodsA bilingual Italian (L1)-English (L2) individual with logopenic-variant PPA completed a bilingual assessment as well as dual-language lexical retrieval therapy (LRT). His bilingual experience was characterized in detail, and therapy outcomes were evaluated within and across languages.

resultsPre-morbidly, the patient was a relatively balanced bilingual individual with stronger L1 literacy. Following disease onset, L2 showed faster decline, whereas L1 remained stable. Age at acquisition, dominance, and language use were among the main factors contributing to his language maintenance and decline. Therapy yielded relatively equivalent item-specific gains in both languages (L1 DISCUSSION: Findings support the relevance of in-depth bilingual assessment and therapy to guarantee successful treatment in PPA, unveiling the relevance of bilingual experience in shaping treatment outcomes.

Indexed as

bilingual experiencebilingual speech‐language assessmentbilingual speech‐language interventioncrosslinguistic transferlexical retrieval therapymultilingualismprimary progressive aphasia

Identifiers

PMID41948541
PMCPMC13052064

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.