Evidence map›Paper›PMID 41948426›Full record

ArticleJournal of ophthalmology2026

Microvascular Changes in Exfoliation Syndrome: OCT Angiography Analysis of Peripapillary Density and Foveal Avascular Zone.

Arzu Karakiraz, Şerife Bayraktar

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arzu KarakirazDepartment of Ophthalmology, Semdinli State Hospital, Hakkari, Turkey.ORCID https://orcid.org/0000-0003-4055-2830
Şerife BayraktarDepartment of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, istanbul.edu.tr.ORCID https://orcid.org/0000-0003-0889-7599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate retinal vascular alterations in unilateral and bilateral pseudoexfoliation by assessing macular and peripapillary vascular density, as well as foveal avascular zone parameters. Patients and Methods: This prospective study included 77 eyes from 39 patients with unilateral pseudoexfoliation, 54 eyes from 27 patients with bilateral pseudoexfoliation, and 50 eyes from 25 healthy controls. All participants underwent OCT-A imaging with the Topcon ImageNet 6 system. Only scans with signal quality ≥ 6/10 were analyzed. Superficial and deep retinal capillary plexus densities were quantified within a 6 × 6-mm macular area, and foveal avascular zone dimensions were manually measured at the superficial plexus. Peripapillary vascular density was also evaluated. Statistical significance was set at Results: Age and gender were comparable across groups ( Conclusion: Pseudoexfoliation is associated with widespread macular and peripapillary microvascular compromise, supporting its bilateral nature even in clinically asymmetric cases.

Indexed as

exfoliation syndromefoveal avascular zoneglaucomapseudoexfoliationvascular density

Identifiers

PMID41948426
PMCPMC13051860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.